Improved glycaemic control by switching from insulin NPH to insulin glargine: a retrospective observational study
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Improved glycaemic control by switching from insulin NPH to insulin glargine: a retrospective observational study
BACKGROUND Insulin glargine (glargine) and insulin NPH (NPH) are two basal insulin treatments. This study investigated the effect on glycaemic control of switching from a NPH-based regimen to a glargine-based regimen in 701 patients with type 1 (n= 304) or type 2 (n= 397) diabetes, using unselected primary care data. METHODS Data for this retrospective observational study were extracted from ...
متن کاملSwitching from premixed insulin to glargine-based insulin regimen improves glycaemic control in patients with type 1 or type 2 diabetes: a retrospective primary care-based analysis
BACKGROUND Insulin glargine (glargine) and premixed insulins (premix) are alternative insulin treatments. This analysis evaluated glycaemic control in 528 patients with type 1 (n = 183) or type 2 (n = 345) diabetes, after switching from premix to a glargine-based regimen, using unselected general practice (GP) data. METHODS Data for this retrospective observational analysis were extracted fro...
متن کاملReduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes.
OBJECTIVE Insulin glargine (LANTUS) is a once-daily basal insulin analog with a smooth 24-h time-action profile that provides effective glycemic control with reduced hypoglycemia risk (particularly nocturnal) compared with NPH insulin in patients with type 2 diabetes. A recent "treat-to-target" study has shown that more patients on insulin glargine reached HbA(1c) levels < or =7.0% without conf...
متن کاملLess Nocturnal Hypoglycemia and Better Post - Dinner Glucose Control With Bedtime Insulin Glargine Compared With Bedtime NPH Insulin During Insulin
DIABETES CARE, VOLUME 23, NUMBER 8, AUGUST 2000 Previous controlled trials comparing various insulin regimens in patients with type 2 diabetes poorly controlled with oral agents have shown that the simple addition of NPH insulin at bedtime (1–3) or of 70/30 premixed insulin (70% NPH insulin/ 30% regular insulin) before supper (4) to previous treatment with sulfonylureas alone (3,2), sulfonylure...
متن کاملGlargine versus NPH insulin in cystic fibrosis related diabetes.
BACKGROUND Cystic fibrosis related diabetes (CFRD) with fasting hyperglycemia is found in 15% of adult and 11% of adolescent CF patients. Because of concerns about hypoglycemia, it is not common practice to treat CFRD with 24-hour basal insulin therapy, despite evidence that insulin deficiency may contribute to protein catabolism and have an adverse effect on weight, muscle mass, pulmonary func...
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ژورنال
عنوان ژورنال: Cardiovascular Diabetology
سال: 2009
ISSN: 1475-2840
DOI: 10.1186/1475-2840-8-3